The 2-Minute Rule for megatomi.com
The 2-Minute Rule for megatomi.com
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Our new Obvious+ tissue clearing approach is the only process that delipidates samples without having alter in morphology and with minimal impact on structural integrity.
Megatome is a vibrating microtome meant to part a broad range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform area profile, and also minimum tissue hurt and data loss.
Antibodies may perhaps get months to diffuse by means of only some millimeters of tissue, using a steep labeling gradient from area to core.
Megatome is suitable for accuracy: the blade vibrates at the next frequency and larger amplitude array than other microtomes, and includes a one of a kind deflection Handle system.
SE works by using a rotational electric area to disperse hugely electromobile molecules (which include antibodies or surfactant micelles) all through a porous sample with no harming electrically charged structures in the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely clear. This allows light-weight penetration into your sample and ensures the acquisition of higher-resolution, in-concentrate picture info.
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eFLASH is really a immediate tissue labeling procedure that enables for uniform complete-organ staining in 20 rounds of labeling.
The SmartSPIM mild sheet microscope gives unparalleled resolution and acquisition velocity through intact tissue volumes, although its modular design lets megatomi.com you up grade and customise specific factors.
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Protect avoids the variability of hydrogel embedding and the information loss from PFA preservation, defending specimens for a number of rounds of processing.
Leverage the Very clear+ tissue clearing system, together with eFLASH and patented stochastic electrotransport systems, to fast apparent and label full organs. Critical highlights and options incorporate:
Our novel Protect tissue preservation system varieties intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.